Centrifuges are widely used in the pharmaceutical industry, and they are still the main equipment for separation in the current API manufacturing process. Due to the different physical and chemical properties of the application, process and medium of the pharmaceutical manufacturer's centrifuge, there are different requirements for the centrifuge, such as anti-corrosion requirements, explosion-proof requirements, medium temperature, and workshop purification level. Let's discuss some of the specific issues involved in filtration centrifuges in the pharmaceutical industry. Sealing requirement Whether the centrifuge is used for non-sterile or sterile drugs, or for pharmaceutical intermediates or for finished drugs, the production process has high requirements for the environment, such as clean workshops. Corresponding to the cleanliness level, the good sealing performance of the equipment keeps the outside and the inside of the machine effectively isolated. However, the solid, liquid, and gas phases in the inner cavity of the centrifuge must not cause pollution to the workshop environment. Conversely, the external environment cannot contaminate the internal materials. Therefore, the pharmaceutical factory should inform the centrifuge manufacturer when ordering and ask for the sealing requirements. The improved design of the sealing performance of the centrifuge is fully reflected in the manufacturing process and should be considered in the following aspects: Sealing of bearing positions <br> Sealing of spindle nut and bearing position. In the previous conventional models, the sealing measures were relatively simple and only relatively sealed. For example, the spindle nut part, the spindle nut and the drum joint surface are generally not provided with a sealing ring. The centrifuge is prone to liquid or gas phase infiltration during operation, causing corrosion to the taper surface of the spindle and even infiltrating into the bearing, causing damage to the bearing. , thus affecting the normal use of the machine. The upper bearing cap is generally provided with a skeleton seal or the like, but a portion between the upper bearing cap and the cone surface of the drum is exposed, and the mist in the inner cavity of the centrifuge may corrode the exposed surface of the spindle. In the centrifuges used in the pharmaceutical industry, most of the materials separated are organic solvents such as solvents or media such as acid and alkali. Therefore, the sealing requirements of these parts should be fully considered when ordering equipment. In the design, the improvement of the above structure should be considered, such as the fastening and sealing of the upper end of the main shaft. Two shaft end retaining rings are stacked, and two O-rings are installed in isolation to eliminate the possibility of liquid leakage. For the seal on the upper side of the upper bearing cap, consider changing the structure of the upper bearing cap, such as setting the labyrinth seal to reduce or eliminate the erosion of the main shaft by the aerosol. It is also possible to apply a nickel-phosphorus alloy to the exposed surface to eliminate or reduce the possibility of corrosion. More attention: squid Ring Squid Ring ZHEJIANG EVERNEW SEAFOOD CO.,LTD , https://www.evernewseafood.com
Sealing of the cover <br> The cover is generally inverted, and the joint between the cover and the casing should have reliable sealing measures. If the sealing structure or material fails to prevent corrosion, it may cause leakage of liquid and gas, and the environment and personnel. cause some damages. The dovetail groove is machined on the flange of the cover, and a sealing strip is installed to ensure the reliability of the positioning of the sealing strip. The sealing strip is a trapezoidal hollow structure to ensure its sealing performance. The sealing strip is made of silicone rubber and other materials, and the sealing strip material is determined according to the anti-corrosion requirements of the processed materials.
Discussion on the special characteristics of pharmaceutical application centrifuge>
Next Article
Things to know about mutton tonic in winter
Prev Article
Western Horsehead goat meat