Aflatoxin b1 characteristics and aflatoxin b1 detector

Aflatoxin b1

Aflatoxin b1 is a derivative of dihydrofuran oxaphthalene containing a difuran ring and an oxaphthalenone (coumarin). Aflatoxin B1 is one of the most carcinogenic among known chemicals. Aflatoxin B1 is highly toxic to humans and several animals, and its toxic effects are mainly damage to the liver. Among the natural foods, aflatoxin B1 is the most common and the most harmful. The AQSIQ stipulates that aflatoxin B1 is one of the necessary inspection items for most foods.

Aflatoxin b1 characteristics:

Aflatoxin can be dissolved in various polar organic solvents such as chloroform, methanol, ethanol, propanol, dimethyl amide, hardly soluble in water, and insoluble in petroleum ether, ether and hexane. Aflatoxin is stable to light, heat and acid. It is only lysed by heating to 280-300 °C. It is autoclaved for 2 hours, the virulence is reduced by 25%-33%, and it is reduced by 50% in 4 hours.

The food contaminated by aflatoxin B1 is mainly peanut, corn, rice, wheat, peanut oil and other foods and oils, and the most polluted areas in the high temperature and high humidity areas in the south. Aflatoxin is heat-resistant and can be cracked at 280 °C, so it is difficult to break under normal cooking and processing temperatures.

Aflatoxin b1 metabolism and toxicity:

The metabolism of aflatoxin B1 mainly occurs in the liver, which is converted into aflatoxin M1, aflatoxin M2, aflatoxin P1, aflatoxin Q1, aflatoxin B2α, under the action of cytochrome P450 mixed functional oxidase. Aflatoxin and other substances. Aflatoxin B1 is converted to aflatoxin M1 (AFM1) by hydroxylation. Aflatoxin M1 is a metabolite of aflatoxin B1, and different animals have the highest AFM1 metabolite content in milk.

CSY-E96H aflatoxin rapid detector

Aflatoxin B1 is 30 times more toxic than vomiting toxin and 20 times more toxic than zearalenone. The acute toxicity of aflatoxin B1 is 10 times that of potassium cyanide and 68 times that of arsenic. Chronic toxicity can induce cancer, and the carcinogenic ability is 75 times that of dimethyl nitrosamine and 900 times higher than that of dimethyl azobenzene. Human primary liver cancer is also likely to be associated with aflatoxin.

Humanity

(1) Human liver cancer and esophageal cancer (aflatoxin), (2) increased susceptibility to disease.

animal

Poultry: (1) feed intake, body weight gain and feed conversion rate reduction; (2) infertility, abortion; (3) pulmonary edema, (4) increased susceptibility to disease.

Pigs: (1) increased feed intake, body weight gain and feed conversion rate; (2) infertility abortion, (3) pulmonary edema, and (4) increased susceptibility to disease.

Cows: (1) feed intake, milk production, body weight gain and feed conversion rate reduction; (2) reproductive performance disorder, embryo death and abortion; (3) nervous system disorders, paralysis and lack of coordination; (4) The susceptibility to disease increases.

Precautions:

1. Industrial feed should control raw materials and keep good feed. B1 and moisture should be tested before entering the factory. The principle that the moisture content of the feed ingredients does not exceed 13% is controlled. If the water content exceeds the standard, it should be dried in time and stored, or the anti-fungal agent should be used. The warehouse of the feed should be kept in a ventilated, cool and dry place. When the ambient temperature is higher than 10 °C, the stacking height should not exceed 4 meters.

2. Do not use moldy feed. Sichuan is hot and humid, and local food is prone to mildew and spoilage. It cannot be used as feed after mold. Some farmers prefer to use biogas residue as feed directly, and they are stacked for a long time and are prone to mildew. Special care should be taken when feeding cows. If you want to use it, you should use it that day. Silage, especially corn silage, is prone to "secondary fermentation" to produce mycotoxins after opening, and special attention should be paid.

3, adsorption method adsorption of mycotoxins: some minerals such as activated carbon, montmorillonite, boronite, zeolite, etc. have a strong adsorption and stable properties, generally insoluble in water, not easily absorbed by animals, added to the feed It can reduce the intake of aflatoxins in livestock and poultry.

4, enzymatic hydrolysis of mycotoxins: feed-grade enzyme preparations, a specific type of biological enzymes that efficiently decompose mycotoxins, including: aflatoxin B1 decomposing enzymes and other enzymes.

Aflatoxin b1 detector Description:

CSY-E96H aflatoxin rapid detector adopts the principle of solid-phase enzyme-linked immunosorbent ELISA, ie, enzyme-linked immunosorbent assay; it can quantitatively detect food, food, feed, oil, dairy products, drugs, beverages, milk, wine and other products. Aflatoxin (B1, B2, G1, G2 M1 M2 AFM1, AFP1, AFQ1, AFB1-2, 3-epoxide) content. And can be connected to food safety monitoring system, aflatoxin rapid detector, drug residue detector is widely used in product quality supervision and inspection, health and epidemic prevention, environmental protection, business management, aquatic products wholesale market, noodle production base, farm, grain Banks, supermarkets, shopping malls, major food safety monitoring systems and other departments.

★ Aflatoxin b1 detector 96 channel design, 9 channel optical system, of which 8 light sources are used for 96-well plate optical signal detection. Another light path is used to calibrate the light source for compensation of the light source system and monitoring of the light source operation.

★High accuracy: It adopts imported special LED light source, which has good wavelength accuracy and repeatability, and comprehensively improves the accuracy of test results.

★ High degree of automation: instrument automatic diagnosis system failure, wavelength calibration: automatic calibration

★ Long service life of the instrument: LED light source, automatic switch energy-saving design, non-continuous working mode. Service life up to 10 years

★ The instrument automatically stores the measurement data. Built-in micro thermal printer, no need to replace the ribbon for life, real-time printing test results test report can print the sample name, aflatoxin content, qualified, date of detection, testing unit. More representative of the authority of the test results, and is conducive to publicity

★Aflatoxin rapid detector The aflatoxin detector has built-in oscillation function, which can edit the oscillation form as needed to promote the thorough mixing of the stop solution to ensure the reliability of the result.

★ Built-in Ethernet card interface, can realize wireless transmission of data, wireless Internet access, sending and receiving mail, etc.

★windows computer operation program, color LCD touch screen operation, easy to operate

★Aflatoxin rapid detector Aflatoxin detector has the functions of query, printing, summary, report, etc. It can directly output the test result, and the software can be upgraded free for life.

★Equipped with RS-232 interface and USB port, data processing, statistical analysis and result uploading can be performed by computer. If you choose the company's food safety monitoring network software, you can set up provincial, city, prefecture, county and other levels of network according to user requirements.

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