J Gerontol: Can coffee inhibit dementia?

J Gerontol: Can coffee inhibit dementia?

Release date: 2016-10-09

Recently, a research report published in the international journal The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences , researchers from the University of Wisconsin-Milwaukee revealed the association between caffeine and prevention of dementia. The researchers found that high levels of caffeine in women aged 65 years and older were directly associated with a lower likelihood of dementia or cognitive impairment in the body.

The study included 6,467 female individuals who had followed the study for more than 10 years and found that individuals with caffeine intake greater than 261 mg had a 36% reduction in the risk of dementia, which is equivalent to daily The amount of 2-3 cups of coffee (8 ounces / cup), 5-6 cups of black tea (8 ounces / cup) or 7-8 cans of cola (8 ounces / can). Researcher Ira Driscoll The professor said that although we can not directly explain the direct relationship between higher levels of caffeine intake and cognitive impairment and the incidence of dementia, we may be able to better clarify caffeine intake through in-depth research. The importance of the body's cognitive health; at the same time, this study not only studies from the perspective of prevention, but also helps people better understand the molecular mechanism of dementia and cognitive impairment.

Researchers know that caffeine binds to pre-adenosine receptors in the brain, so this study highlights a potential mechanism to help us delve into the causal relationship between caffeine and cognitive impairment. The more evidence suggests that caffeine intake can act as a protective factor against cognitive impairment, which may indicate that caffeine is also an easily modified dietary factor. In this study, researchers studied the association of women with different amounts of coffee over time to examine the association between caffeine intake and the risk of dementia.

Using data from 6,467 menopausal women aged 65 years and older, the researchers used questionnaires to assess participants' caffeine intake. The questionnaire included: coffee, tea, and cola beverage intake, including Frequency and intake, etc. In an annual cognitive assessment functional test of 10 years or less, 388 of these participants underwent a diagnosis of a possible dementia or some form of cognitive impairment testing. Researchers hope to explore the specific associations between coffee intake and dementia and related mechanisms through more in-depth research.

Source: Bio Valley

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