Found 939 new genes related to human intelligence

Britain’s “Nature and Genetics” magazine published on the 24th two important human genetics research results: a team of European scientists genetically analyzed more than 250,000 individuals and 500,000 individuals, identified hundreds of intelligence and neuroticism A new genetic locus. This result greatly broadens the human understanding of cognitive functions.

The inheritance of intelligence is very complicated. Scientists previously believed that perhaps no single gene can have a huge impact. However, the genetic quality is the biological premise of intellectual development. We must gradually uncover the genetic loci related to intelligence so that we can further understand the neurobiological basis of intelligence at the molecular level. Depressive disorder, a psychiatric disorder, is characterized by significant and persistent mood depression as the main clinical feature, also known as depression. So far, the etiology of depression is not yet clear, but it is already certain that biological factors are involved in the pathogenesis of depression—a factor that mainly involves genetics, neurobiology and other aspects.

In one of the studies, Danielle Possmann, a scientist at the Free University of Amsterdam in the Netherlands, and colleagues first analyzed genetic data and intelligence measurement data for more than 250,000 individuals and found 190 new genetic loci related to intelligence. And 1016 specific genes - of which 939 are new discoveries. According to analysis, the research team proposed that intelligence can increase or prevent Alzheimer's disease and hyperactivity disorder (ADHD). They also identified genetic pathways related to nervous system development and synaptic structure.

In another study, the research team focused on an important risk factor for neurotic depression and schizophrenia. They analyzed about 500,000 individuals and identified more than 500 genes related to neuroticism. The research team described two different neurotic genetic subgroups, one related to depression and the other related to trouble.

Taken together, these two studies provide new insights into the neurobiological and genetic basis of human understanding and cognition. Researchers believe that these latest data will help future studies related to neuropsychiatric disorders.

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