With the rapid development of gene sequencing technology, the generation of genetic data has increased exponentially, and higher requirements have been placed on detection speed and analysis ability. Recently, Shenzhen Chengqi biological cloud computing platform, equipped with the independent research and development of the three generations of FANSe algorithm, has set a record in the world, the first time to achieve a minute to analyze nearly 20,000 genetic information of a person, dozens of times faster than the same technology The accuracy is even more amazing. This technological breakthrough indicates that the speed and cost of genetic testing will achieve a qualitative leap, and the era of precision medicine for all will accelerate. FANSe third generation algorithm spikes other algorithms Each person's genome consists of 6 billion bases and encodes more than 20,000 genes. People's lives and deaths are among these gene sequences, and each person is different. Therefore, the basis of precision medicine is large-scale genome sequencing. With the rapid advancement of large-scale sequencing technology, the sequence of measuring more than 20,000 genes can be as fast as a few hours, but the analysis of this massive amount of genetic data has been calculated in the past. In order to avoid the "sequence of five minutes, two hours of operation", the previous solution was nothing more than the use of supercomputers, or the development of dedicated acceleration chips to accelerate, but the resulting high cost, poor flexibility, accuracy The problem is not high, and it has been criticized by the medical profession. In order to overcome this problem, Shenzhen Chengqi Biotechnology Co., Ltd. (hereinafter referred to as Chengqi Bio) has spent three years fully researching and developing the high-precision FANSe third-generation algorithm and the sequencing data analysis cloud platform, which will be in 58 seconds. The analysis of hundreds of millions of bases of nearly 20,000 genes in one person has set a new world record. "We are working with Tianhe No. 2 supercomputer. If necessary, it will take ten days to fully calculate the genetic information of 1.3 billion people in China." Professor Zhang Gong, developer of FANSe algorithm, said that there is no need to accelerate the characteristics of the chip. Make this program easy to promote. The system developed by Chengqi Biotech is not only amazing, but also greatly improves the accuracy. At the beginning of the algorithm design, Professor Zhang Gong set a demanding goal. “The analysis error should not exceed one hundred million in any case, surpassing all traditional algorithms.†It really did. A large number of experimental verifications show that the FANSe series of algorithms have an accuracy of almost 100% in applications such as DNA mutation analysis and RNA expression analysis. They have spiked foreign programs based on BWA and Bowtie algorithms, and have accumulated many successes in medical research and clinical practice. In the case, I found a suitable targeted drug for patients with advanced pancreatic cancer within 5 days. The cumulative number of scientific research/clinical cases was more than 20,000. In November 2017, Chengqi Bio has published a paper in the top journal of the international nucleic acid research field and the British Journal of Nucleic Acid Research. With this system, the second-order analysis of the human transcriptome has been successfully realized, that is, more than 1 second. The analysis of the complete human transcriptome sequencing data in the time, and free to open to researchers around the world, set a new world record for sequencing analysis. Cloud platform has completed genetic analysis of more than 500,000 samples Since scientists began decoding the human genome in 1999, doctors have predicted the era of " precise medical care ." With the development of gene sequencing technology and medical science, medical treatment is gradually moving toward the era of personalized precision medicine. Ms. Chen was diagnosed with breast cancer. She was afraid of the side effects caused by improper selection of chemotherapy drugs. She was enrolled in the comprehensive sequencing of more than 20,000 genes in Chengqi. On the day of sequencing completion, the cloud platform quickly analyzed its genetic data and found that the docetaxel in the doctor's original drug regimen had poor efficacy and side effects. After patient communication with family members and doctors, the doctor adjusted the medication plan according to Ms. Chen's genetic test results, using a combination of the accurately calculated recommended chemotherapy drug epirubicin plus cyclophosphamide. After two phases of chemotherapy, the effect was very significant, and the tumors shrank. Ms. Chen did not feel obvious discomfort. Instead, the amount of rice increased, her sleep was more fragrant, and her face was red. "I don't see that she is a cancer patient receiving chemotherapy." Ms. Chen's daughter said happily. Precision medicine is a privately customized medical model. Based on human genome information, it combines relevant internal and environmental information such as proteome and metabolome to develop optimal treatment plans for patients, including medication protocols, in order to maximize therapeutic effects and minimize side effects. The reporter learned that Chengqi Bio's high-speed analysis cloud platform has analyzed more than 500,000 samples in medical research and clinical applications, looking for the cause of rare infectious diseases, finding suitable drugs for patients with advanced cancer, and the results are It is desirable to save a lot of lives. It is also because of these achievements that Professor Zhang Gong, the developer of FANSe algorithm, has become one of the few Chinese scientists in the genetic sequencing field who are invited to give TED speeches. “After a minute, nearly 20,000 genetic information can be analyzed, which means that the analysis of large-scale sequencing will no longer be a bottleneck.†Professor Zhang Gong said that with the help of these new technologies, people will do genetic testing in the near future. More convenient and fast, cheap and good, the era of precision medicine for all will be just around the corner. (Southern Network) Small O2 N2 Generator,Nitrogen Generation System,Nitrogen Machine,O2 Generator Hangzhou Zhongju air separation equipment manufacturing Co., Ltd , https://www.hzzjkfzz.com
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