Population X-ray mammography screening rejected in Switzerland

Population X-ray mammography screening rejected in Switzerland

Release date: 2014-05-06

In the past 10 to 15 years, the controversy about mammography photography has been endless. At present, more than 75% of women aged ≥ 50 years in Switzerland receive at least one mammography test in their lifetime. In January 2013, with the support of the Swiss Ministerial Conference, the Swiss Medical Association and the Swiss Academy of Medical Sciences, the Swiss Medical Council launched an independent health technology assessment program for mammography screening, mainly by medical ethicists and clinical epidemics. The specialists form experts to assess existing evidence and practical applications, and other members include clinical pharmacologists, oncologists, nursing specialists, lawyers, and health economists.

On February 2 this year, the Swiss Medical Council released a report that systematic mammography screening did not significantly improve the overall mortality of breast cancer patients, especially the false positive results and over-diagnosis hazards; no longer accept new The screening system, while existing mammography screenings will be phased out; it is required to assess the quality of various forms of mammography screening and provide accurate benefit and risk information. Once published, the report caused a sudden and categorical rejection among Swiss oncologists and related organizations, and was even labeled as "immoral" by some people. One of the biggest controversies is that it runs counter to the global consensus appointed by leading experts in the field. Again, it will make women feel overwhelmed.

On April 16th, the New England Journal of Medicine published the main findings and expert opinions of the Swedish Medical Council online.

* The trial of mammography screening dates back to a study completed by a New York scholar more than 50 years ago, and the last clinical trial of that period was reported by a British scholar in 1991. At that time, modern breast cancer treatments that have been shown to significantly improve patient outcomes have not yet been developed. Thus, between 1963 and 1991, mammography screening did have a slight benefit in reducing mortality in breast cancer patients.

* The vast majority of the panel believes that mammography screening can reduce the relative risk of death in breast cancer patients by nearly 20%, but there may be over-diagnosis. The recently released Canadian International Breast Cancer Screening Study once again corroborates the hazard: After 25 years of follow-up, the researchers found that 21.9% (106/484) screening suggests that breast cancer patients are over-diagnosed, meaning they accept unnecessary Breast cancer interventions such as radiotherapy, chemotherapy, surgery or combination therapy. In addition, the Cochrane systematic review of more than 600,000 women in 10 clinical studies did not show mortality gains from mammography screening. From a positive perspective, this negative result may be due to the reduction of mortality associated with mammography screening by other causes of death; from a negative perspective, the result has actually corrected other confounding causes, mammograms Molybdenum target screening does more harm than good.

* A survey of 1,003 50-year-old American women showed that 71.5% of respondents strongly believe that mammography screening helps to reduce breast cancer mortality by at least half, and 72.1% of respondents believe that mammography The investigation can save at least 80 of the 1,000 women. It is obvious that people have high hopes for mammography screening. However, this good vision has not been realized. Mammography screening can only reduce the relative risk of breast cancer death by 20%, and only prevent one death from breast cancer. In the United States, to prevent a case of breast cancer death, women are required to undergo mammography screening every 2 years starting at age 50 and for 10 years, but 490 of 670 women may have false positive results. Repeatedly, 70 of 100 women may have undergone unnecessary biopsies, and 3 of 14 women may have been overdiagnosed with breast cancer without clinical signs (Figure 1).

Reporter NikolaBiller-Andorno responded that if breast X-ray mammography screening can detect breast cancer early and save the patient's statement, we must strongly support it, but this is not the case. Therefore, it should be routinely applied based on the individual needs of the patient, rather than in a cage. From a moral point of view, we cannot agree with a public health project that still does not have a clear advantage over its disadvantages. Trying to clarify disputes, improve services, and avoid over-diagnosis is the best way to screen mammography.

Source: "Medical Cancer Channel" Micro Signal

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