Functional principle and application of SONICS ultrasonic cell disruptor

Functional principle and application of SONICS ultrasonic cell disruptor

Instrument Name: Ultrasonic Cell Breaker

Configuration : ultrasonic breaker host + probe + operation manual + tool kit

Working principle : The power converter of the ultrasonic cell crusher converts the commercial voltage of 50/60 Hz into high-frequency electric energy, and delivers the high-frequency electric energy to the piezoelectric transducer in the converter, in the piezoelectric exchange The energy is converted into mechanical vibration, and the probe strengthens the mechanical vibration emitted by the transducer and transmits it to the liquid in the form of ultrasonic waves. This action forms thousands of microbubbles (holes) under negative pressure. Expansion, and bursting during positive pressure, this phenomenon is called cavitation. It releases a lot of energy at the point of explosion and produces a strong shear on the probe tip. The larger the tip of the probe, the larger the volume that can be processed, but the smaller the strength.

Simply summarized as: electrical energy - mechanical energy - negative pressure (expansion) - positive pressure (explosion)

Function: American SONICS ultrasonic cell crusher is a multi-purpose ultrasonic shatterer for various research fields. It can process organic and inorganic samples from hundreds of microliters up to several hundred liters, and can break various cells and bacteria. Spores, tissues, and can break up the polymer, emulsifie the sample, dissolve the insoluble matter, accelerate the reaction speed of chemical, biological, physical, atomize the liquid, disperse the particles, prepare the sample, vaporize the liquid, and the like.

Application areas:

Biology: animal, plant cells, E. coli, yeast, streptococcus, staphylococcus and other life science research departments

Medicine: Breaking of microbiological test samples (use in laboratory, microbiology, etc.)

Agronomy: extraction of subcellular structures such as chloroplasts, extraction of plant proteins and nucleic acids, etc.

Pharmaceutical: EPO (erythrocyte growth factor) and other transgenic cells, bacterial disruption, new drug development department

Materials Science: Preparation and dispersion of nano and micro materials

Chemistry: Polymerization, molecular weight change, etc.

Physics: emulsification, cleaning, dispersion, defoaming, etc.

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