Sweat perception will be the next smart health wear hotspot, the US Air Force has invested $4 million

Sweat perception will be the next smart health wear hotspot, the US Air Force has invested $4 million

Release date: 2016-10-21

Recently, sweat-sensing technology has become a hot segment of smart wearable devices, and the US Air Force and the Rugby League NFL have participated in it. On October 8, sweat sensor developer Eccrine Systems announced a $5.5 million Series A round of financing, of which 4 million came from the US Air Force. On October 18th, another liquid water sensor developed by GraphWear, a smart wearable device company, announced that it has cooperated with the NFL of the American Football League to carry out technical verification and auxiliary research and development.

Science in sweat

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Smart wearable devices help us understand and monitor our physical condition by collecting physiological data from the human body. From simple stepping to traditional heart rate, body temperature, and now sweat analysis, smart wearable devices are beginning to track more and more human physiological data. Do not underestimate the sweat. In addition to salt, a drop of sweat contains various scientific codes in our body, including hydration levels, electrolyte balance, lactate index, blood sugar levels, and calorie burning values. Researchers believe that by measuring various electrolytes, metabolites and other components in sweat, combined with the user's body temperature, heart rate and other data, more accurately analyze the user's physiological conditions, determine whether it is in fatigue and dehydration, timely to the user Reminder to prevent excessive exercise.

At present, most of the smart devices for analyzing sweat have not yet been commercialized, and the detection sensitivity, the size of the device, and the combination and practicality of the human body are problems that need to be broken. It is common to use body fluids to detect physical conditions. Most hospital tests rely on various body fluids, but sweat with a lot of life information has not been selected. Major scientific research institutions want to make further breakthroughs in sweat sensing technology to achieve non-invasive testing.

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In August of this year, postdoctoral researcher of the University of California, Berkeley, boarded the MIT Science and Technology Review's annual youth hero list with a fully flexible sweat sensor. The Javey Research lab, composed of Gao Wei and instructor Ali Jiewei, saw the possibility of non-invasive testing in the sweat on the future. The chemical composition of sweat is diverse and easy to obtain. In the initial version of the sweat sensor, their design set five detection dimensions: glucose, lactic acid, sodium ion, potassium ion and body surface temperature, and also continuously added heavy metal, chloride ion and other detection objects. These specific test objects can peek into the secrets of the body. Gao Wei said that it is already medically convinced that sodium ions in the blood can detect the dehydration of the body. Chloride ions can be used to diagnose cystic fibrosis. For example, glucose in the human body is related to glucose in the blood. Can be used to detect diabetes.

In addition to the university's scientific research institutions to decode the secrets of sweat, there are also many start-ups that are launching or preparing to launch sweat-related devices and have gained the favor of capital.

Eccrine Systems

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Eccrine Systems is a privately held company established in 2013 and headquartered in Cincinnati, Ohio. The company is committed to improving human health, safety and productivity through sweat sensor technology. Its commercial technology and intellectual property are from the University of Cincinnati and are supported by CincyTech. On October 8, the company announced the completion of a $5.5 million Series A financing. Company co-founder and CEO Robert Beech said at a press conference: "Sweat is the best source of non-invasive means of obtaining molecular data and physiology data. In the medical world, these data were previously obtained from the blood. The application of sweat is often limited by the lack of real-time data in the daily life of the human body, including work, sleep, entertainment, etc. Today, microfluidics, nanotechnology, Advances in technologies such as microelectronics and energy management have made it possible to monitor sweat molecules in real time through sensing systems."

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The US Air Force is also very interested in the study of sweat, and Eccrine has funded $4 million for a future five-year research program that provides real-time body monitoring and functional enhancement training for ground forces soldiers and pilots. Researchers at the US Air Force want to use a reliable means of studying the molecular level and quantification of the body, but not by blood. Researcher Joshua Hagen said that the laboratory has now tested multiple prototypes in US special forces and is the earliest adopter of the technology.

Of course, sweat can also help researchers study the physiology of pilots. For example, the US Department of Defense collects a large amount of data from billions of dollars of fighters (F-22 and F-35 fighters), but the data is Revealing the physical condition of a pilot who is under high pressure in an aircraft does not provide too much valid information. Determination of a component of the sweat called cortisol is currently a key study of Eccrine, a hormone that acts as a key stress marker in the body. Dehydration status and cortisol testing are the first important tasks for sweat monitors in pilots, and this will be done in the next 2-4 years.

Financing situation

Eccrine was founded by Jacob Heikenfeld, a professor at the US Air Force and the University of Cincinnati. The company's chairman is a former naval member and another executive is a former air force pilot. $5.5 million in Series A funding, $4 million from the US Air Force Research Laboratory to support the development of non-invasive sensing systems that monitor specific molecular biomarkers in sweat. The CincyTech Fund and other investors are also involved in this round of financing.

Graphwear

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Graphwear is from the University of Philadelphia City Science Center and is incubating by the famous DreamIt Ventures to develop smart wearables. SweatSmart is the first product to perform real-time analysis using sweat for dehydration monitoring, glucose testing, and muscle endurance monitoring. Graphwear reached a partnership with the NFL in October (NFL also invested in another sweat smart device company, Kenzen) to alert athletes to liquid replenishment by analyzing athletes' sweat blood sugar and electrolyte levels. Graphiff CEO Gudibande said: "Professional athletes will help us verify the technology, we also need to collect more data to improve the stability of the product." Graphwear plans to launch a beta version of the athletes in May next year, listed in 2018. The company will also launch a new product that tracks blood sugar through sweat in the future. This product is aimed at the diabetic population and is a Class 2 medical device that requires FDA approval.

SweatSmart uses graphene instead of silicon-based sensors. Graphene is flexible and can be bent at will, so it is more comfortable to wear on the human body. Moreover, the graphene sensor is also very sensitive to bioelectricity and can detect changes in the body's tiny signs. As for power consumption, graphene batteries will also bring a breakthrough life experience. Although graphene has been discovered for nearly a decade, GraphWear still took 23 processing steps to make graphene sensors, so mass production is impossible, and its cost is extremely expensive. The initial product price is estimated to be 60,000 US dollars.

Financing situation

Received a seed investment of 50,000 US dollars, the investor is unknown.

Kenzen

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Kenzen is a company specializing in the development of sweat smart devices, and the product has been iterated twice. The current product model is ECHO Smart Patch. The product monitors the sweat components of the body in real time and requires minimal sweat to perform critical biomarker analysis. In addition to water, it also analyzes electrolytes such as sodium, metabolites, glucose, various molecules and proteins. Using the ECHO Smart Patch not only prompts the user to replenish moisture, but also further informs the user of vitamins and minerals that are lacking in the body. In the future, it will also help users balance the body's sugar intake and ensure that the body does not accumulate too much fat.

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This product is small in size, low in power consumption, and needs to be in close contact with the skin. It can monitor changes in sweat chemistry at any time and transmit this information to the smartphone via Bluetooth. Therefore, in the future, it is likely to cooperate with sportswear to become a so-called smart sweat-type smart clothing.

Financing situation

In February 2016, Kenzen was led by the NFL, the NFL, and the $50,000 seed round invested by Connectivity Capital Partners and Kii Corporation.

Neumitra

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Neumitra was founded in 2009 by Robert Goldberg, a neuroscientist who graduated from the Massachusetts Institute of Technology. His other two co-founders are computer algorithm engineer Safiyy Momen and biotechnologist Anand Yadav, based in Boston, USA. The company develops smart wearables that help people measure and manage the impact of everyday activities on brain health and performance. The smart device launched by Neumitra is used for psychological stress perception. When the body is stressed, it will inexplicably feel shortness of breath and rapid heartbeat. Neumitra's equipment detects the increase in sweat and body temperature caused by stress or excitement and transmits information to the wearer.

Neumitra has launched three products, wearables, desktop computing systems and mobile apps, to manage brain health and measure its impact on everyday life by co-integrating data. Currently, the wrist-worn sensor Neuma is priced at $1,500. The sweat gland and the pressure response are controlled by the same part of the nervous system. That is, by measuring the electrical conductivity of the skin of the fingers, palms and feet, we can partially understand the stress conditions that the body is currently subjected to. In general, the more sweating, the stronger the skin's conductivity, and accordingly, the higher the brain's pressure. Therefore, skin conductivity can be used as an indicator of brain pressure.

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Neumitra's method of use is very simple, users need to wear the wrist-worn sensor Neuma, which will accurately and continuously measure the data of the autonomic nervous system in each of the daily life situations. Next, the front and back data measured by Neuma, such as events, locations and activities, will be analyzed and analyzed by the supporting mobile app to discover some autonomic symptoms and determine the cause. When the sensor detects signs of pressure, it alerts the wearer by vibration, so we can prepare in advance to avoid places and scenes that may cause anxiety.

Financing situation

In October 2010, he accepted a seed round financing that was not announced. In June 2012, Rock Health invested in a seed round of $20,000. In August 2015, an undisclosed amount of angel round investment was accepted, and the investor was TechNexus EMERGE Accelerator. ( Liu Zongyu )

Source: Arterial Network

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