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Researchers develop "capsule vaccines" that can immunize all diseases
[ China Pharmaceutical Network Technology News ] From the birth of a child, almost one month within one year of age, you have to go to a community health service center to vaccinate your baby. Is there a way to put all the vaccines into one system and realize the immune system for all diseases?
As a professor at the Massachusetts Institute of Technology (MIT), Robert Langer has the largest laboratory in the United States (more than 100 people in the laboratory), more than $10 million in research and development funding per year, and his laboratory to study targeted drug delivery systems and tissue engineering. Famous, he has published more than 1,200 professional papers and applied for more than 900 patents, of which more than 400 have been authorized. Recently, his team has developed a technology that promises to immunize all children with only one injection.
It is understood that they store the vaccine in microcapsules, release the initial dose from the first time, and then start the booster at a specific time to release the immune active substances against different diseases, thereby achieving immunity against all diseases. This method has been published in the journal Science and has been used in mouse trials that are expected to help patients around the world.
Immunization program in China
Every child immunization means tears and screams, and this frequency is high. For example, diphtheria, tetanus, whooping cough, poliomyelitis, inactivated vaccine for JE and hepatitis B, pneumococcal vaccine... This has increased children's fear of injections, and on the other hand has increased the troubles of parents.
The new particles designed by Professor Robert Langer's team can combine all the reagents into one injection. The mouse test shows that their contents can be released after 9 days, 20 days and 41 days after the injection, and released after hundreds of days. Particles have also been developed. However, this method has not been tested on the human body.
Professor Robert Langer said: "We are very excited about this work. This is a major breakthrough in the conventional immunization program. We created a library of tiny closed vaccine particles, each of which can be released in an accurate and predictable time, although It's just a single injection but actually contains multiple built-in boosters. This has a major impact on patients around the world, especially in developing countries."
Reference materials:
Every childhood vaccine may go into a single jab
DNA 'vaccine' sterilizes mice, could lead to one-shot birth control
Original title: Researchers develop "capsule vaccines" only need to be vaccinated once
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