New study finds that vitamin D deficiency is associated with an increased risk of diabetes May 9, 2018 Source: CPhI Pharma Online Author: The red leaf The main role of vitamin D is to maintain bone health. A large number of studies have found that vitamin D can act on a variety of tissues and organs, and is closely related to the occurrence of cancer, autoimmune diseases, hypertension, and tuberculosis. An epidemiological study conducted recently by researchers at the University of California, San Diego School of Medicine and Seoul National University has shown that a lack of vitamin D can significantly increase the risk of developing diabetes. The results of the study were reported in the online edition of PLOS One magazine on April 19, 2018. The researchers studied a cohort of 903 healthy adults with no pre-diabetes or diabetes signs from 1997 to 1999 and followed them up to 2009. At the time of follow-up, their blood vitamin D levels, fasting blood glucose, and oral glucose tolerance tests were tested. During this period, there were 47 new cases of diabetes and 337 cases of pre-existing diabetes (ie, blood glucose levels were higher than normal, but not enough to be classified as type 2 diabetes). In the present study, the researchers determined that the minimum healthy level of 25-hydroxyvitamin D in plasma was 30 ng/ml (30 ng/ml). This indicator is 10 ng/ml higher than the value recommended by the Institute of Medicine currently affiliated with the National Academy (the federal government's health advisory body) in 2010. However, many research teams have suggested that healthy serum vitamin D levels should be higher, with a maximum recommended index of 50 ng/ml. This is still a very controversial topic. Participants found that participants with blood levels of 25 hydroxyvitamin D above 30 ng/ml had a two-thirds reduction in diabetes risk, while participants who achieved 50 ng/ml had a four-fifth risk of diabetes. Research collaborator, Cedric F. Garland, a visiting professor of family medicine and public health at the University of California, San Diego School of Medicine, says that people with 25-hydroxyvitamin D levels below 30 ng/ml should be considered vitamin D-deficient. The researchers found that these people were five times more likely to develop diabetes than people with 25-hydroxyvitamin D levels above 50 ng/ml. Garland has previously studied the relationship between vitamin D levels and various types of cancer, he said, based on previous epidemiological studies that vitamin D deficiency is associated with a high risk of diabetes. Epidemiological studies analyze the distribution and determinants of health and disease states. This kind of research is not enough to prove causality. Garland, the study's author, said that further research is needed to determine whether high levels of 25-hydroxyvitamin D can prevent type 2 diabetes or prevent conversion from pre-diabetes to diabetes, but both this paper and past studies suggest a strong association between the two. Sex. Garland and other researchers have long advocated the benefits of vitamin D for human health. In 1980, he and his late brother, epidemiologist Frank C. Garland, published an article about vitamin D (produced by the sun from the human body) and calcium (absorbed by the body with the help of vitamin D) to lower the colon. An important paper on cancer risk. Garland brothers and colleagues then found that they are associated with breast, lung and bladder cancer. Garland says that to achieve a 25 ng/ml level of 25 hydroxyvitamin D, you need to take a daily intake of 3,000 to 5,000 international units (IU) of vitamin D. If you can get moderate sun exposure at least every day (every day at noon outdoor sunshine) For about 10-15 minutes under intensity, you only need a lower dietary intake. The average daily vitamin D intake recommended by the National Institutes of Health is 400 IU for children before 1 year old, 600 IU for women aged 1 to 70 (decrease for pregnant or lactating women), and 800 IU for people over 70 years old. It is generally believed that it is safe to take higher doses of vitamin D daily, but if serum levels exceed 125 ng/ml, adverse side effects such as nausea, constipation, weight loss, heart rhythm problems and kidney damage may occur. In-depth study of vitamin D will provide new ideas for the treatment of type 2 diabetes and its complications, especially vitamin D analogues, which play a role in metabolism and immune regulation under the premise of reducing the influence on electrolytes, which deserves further investigation. Reference source: Vitamin D deficiency linked to greater risk of diabetes Polysaccharide is a glycosidic bond bonded sugar chain, at least more than 10 monosaccharides composed of polymerized sugar polymer carbohydrates, can be used in the general formula (C6H10O5) n said. Polysaccharides composed of the same monosaccharides known as homopolysaccharides, such as starch, cellulose and glycogen; polysaccharides composed of different monosaccharides known as heteropolysaccharides, such as gum arabic is composed of pentose and galactose. Polysaccharide is not a pure chemical substance, but a mixture of substances with different degrees of polymerization. Polysaccharides are generally insoluble in water, have no sweet taste, cannot form crystals, and have no reducibility or change of spin. Polysaccharides are also glycosides, so they can be hydrolyzed, and in the process of hydrolysis, they tend to produce a series of intermediate products, and eventually completely hydrolyzed to obtain monosaccharides. Edible mushroom polysaccharide;Wolfberry polysaccharide;Jujube polysaccharide Shaanxi Zhongyi Kangjian Biotechnology Co.,Ltd , https://www.zhongyibiotech.com
New study finds that vitamin D deficiency is associated with an increased risk of diabetes
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