Japanese team cracked Ebola virus structure November 09, 2018 Source: Ministry of Science and Technology According to a report in the Nikkan Kogyo Shimbun, researcher Sugita Sakuhiko of the University of Okinawa University of Science and Technology has cracked down on the detailed structure of the complex formed by the binding of ribonucleic acid (RNA) and nuclear proteins in the Ebola virus genome. The results were published on October 18, 2018 in the online edition of the British science journal Nature. This brings hope to the next development of related therapeutic drugs for Ebola hemorrhagic fever. The researchers expressed Ebola virus nucleoproteins in human cultured cells and artificially synthesized a complex of RNA and nuclear proteins, followed by low-temperature electrons with a resolution of 3.6 angstroms (1 billionth of a billion meters). The microscope analyzes its structure at the atomic level. The analysis results show that the RNA nucleotide with 6 molecules binds to the specific amino acid of the nuclear protein through electrostatic interaction while binding to one molecule of nucleoprotein. In addition, the research team also clarified that the amino acids at the junction between the proteins forming the helical structure are charged, and they maintain a compact spiral structure by electrostatic bonding. The Ebola virus causes a serious systemic disease, Ebola hemorrhagic fever, with a mortality rate of 90%. Its prevalence is mainly concentrated in West Africa, and by 2016 it has caused more than 10,000 deaths. However, to date, there has been no effective method of prevention and treatment. At present, cases have occurred in areas outside Africa, and Ebola has become an important global issue. Bio mat,Amethyst mattress,Far infrared ray amethyst mats,Amethyst heat mat Guangzhou Fuerle Health Technology Co., Ltd , https://www.fuerlegroup.com
Japanese team cracked Ebola virus structure