An active substance is the main active ingredient in a drug. Take a simple aspirin for example. Acetyl salicylic acid is synthesized through chemical process and purified to a specified purity. The synthesis of acetyl salicylic acid is made by adding various excipients, such as fillers, adhesives, disintegrating agents, etc., and then pressing it into tablets. The production of apis is generally either pure chemical synthesis, biological fermentation, or semi-synthesis, with biological fermentation followed by extraction followed by synthesis. Not all pharmaceutical enterprises make API by themselves, and many manufacturers do not have the scale to produce API. Even if there is large-scale production, the cost of production may be much higher than that of procurement. Therefore, most manufacturers buy bulk drugs, and then make preparations, so that the production of drugs can be completed without a very large scale. At present, China and India have become the two largest API producers in the world. Many European and American pharmaceutical companies, even some of their own original drugs, will give up the production of API as the patent expires and the market matures, and turn to purchase apis from China and India,API production generally go through laboratory, generated through laboratory bottle container canister, taking after successful, pilot magnification, which is to enlarge the quantity of the production, then no problem tends to be faced with a lot of small scale experiment, a very simple example, the heating process, due to the relatively small amount in the laboratory, uneven heating cases is less, But if it is scaled up to a few tons of pot, at this time the heating may be not hot in this place, where the paste pot, at this time you need to stir, but the speed of mixing is appropriate, this process needs to calculate or grope. Finally from the pilot test, and then to the formal production, the volume of further amplification, and will face a lot of new problems. Therefore, although some drugs are generic, the research and development of the whole process from small test, pilot test to the final mass production is indispensable, so even generic drugs have very high research and development costs. api meaning,api products to buy,best api products,cheap api products,best buy products api,best api products Shaanxi YXchuang Biotechnology Co., Ltd , https://www.peptidenootropic.com
2. Concealer settings. In the pond, water hyacinths, water peanuts and other aquatic plants are transplanted as hidden objects, accounting for about 1/6-1/5 of the pond area.
3. Fish species. The species of fish is 10 cm in size and is free from disease and injury.
4. Fish feed. The black mullet species were found in Xiatang in early April, with a stocking density of 6,000 fish/667 square meters. The two ponds were all put on foot once and the total stocking capacity was 60,000. The fish species shall be disinfected with 667 square meters of fresh lime and 75 kilograms of clear ponds for 15 days before stocking. When stocking, the fish body shall be sterilized with a concentration of 4% salt water.
5. Feed the bait. In the early days of the fish ponds, the bait is cut into puffs and fed. When the fish grows to a larger size, it can also be fed directly. Adhere to the "four determinants" feeding, feeding 2-3 times a day, the daily feeding amount of pond fish body weight of 6% -8%, and depending on the fish's food, weather, water quality and other conditions increase or decrease. Feeding can not be interrupted, but in the event of abrupt changes in the weather, water quality deterioration or fish activities are not normal, take measures to reduce or stop feeding.
6. Water quality regulation. It is necessary to adjust the water level and water quality in a timely manner. In particular, fresh water should be injected once every 7-10 days in the hot season, adding 15-20 cm of water each time. At other times, new water is injected every half month, and the transparency of groundwater is always kept at 25-35 cm. In case of bad weather and when the fish floats, open the aerator to increase oxygen. At the same time, 20×10(-6) lime water is splashed once every 20-30 days to improve water quality and prevent fish diseases.
7. Fish disease prevention. Take precautions as the main factor, strictly control the bait feed, ensure that the bait is fresh and clean, feed after disinfection, and disinfect the lime once a week at the bait station. From April to April, it is pre-preservative skin disease, 1 g of bleaching powder is splashed once per cubic meter of water; in May-September, 1 g of bleaching powder is splashed every cubic meter of water body every 30 days to prevent bacterial gill disease. 1 time. Fish disease was diagnosed in a timely manner and the disease was prescribed.
The total area of ​​this project is 0.66 hectares, and it is arrested at the end of the year. The average output per 667 square meters has reached 5,658 kg and the survival rate is 94.3%. Total income is 1.069 million yuan, and net profit is 658,000 yuan.
High-yielding Techniques for Single-cultivated Chinese Wolfberry in Pond >
1. Pond conditions and supporting facilities. Two ponds, each with an area of ​​0.33 hectares, a pool depth of 1.8 meters, a water depth of 1.5 meters, a bottom soil of loam, a mud thickness of 10 centimeters, convenient irrigation and drainage, adequate water sources, no pollution, and production facilities, water The electric, road, and management rooms are complete, and a 1.5-kilowatt aerator is equipped for each pond.
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