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Generic Name: Paclitaxel
Brand Name: Abraxane
CAS: 33069-62-4
Appearance: White crystalline powder
Paclitaxel Function:
1. Paclitaxel is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Paclitaxel has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma. Â
4. Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents.
Paclitaxel is Used for:
Treating breast cancer in certain patients. It is also used along with carboplatin to treat non-small cell lung cancer in certain patients. It is also used along with gemcitabine to treat cancer of the pancreas. It may also be used for other types of cancer as determined by your doctor.
Paclitaxel is a chemotherapy medicine. It works by slowing or stopping cancer cells from dividing and growing, so they eventually die.
Paclitaxel Application:
1. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is also used for the prevention of restenosis.Â
2. Paclitaxel stabilizes microtubules and as a result, interferes with the normal breakdown of microtubules during cell division. Together with docetaxel, it forms the drug category of the taxanes .
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Name
Paclitaxel
Brand Name
Abraxane
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