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Basis information
Name:AP26113
CAS:1197958-12-5
Molecular Formula:C27H36ClN6O4P
Molecular Weight:575.039301
Color:White powder
Purity:98%min
Usage: Pharmaceutical intermediates
Related Categories:Signal transduction pathway kinase inhibitor; cell signaling pathway inhibitor; protein tyrosine kinase; pharmaceutical intermediates; API; small molecule inhibitors; small molecule inhibitors, natural products
Packaging Details:on request
Delivery Detail:Shipped in 3Â days after payment
Quick details
Â
Minimum order quantity
100g
Price
Negotiable
Lead time
within 24 hours upon receipt of payment
Delivery time
About 7Â days
Packaging Details
Aluminum Foil Bags or Fiber Drum
Payment Terms
T/T,West Union, Money Gram, BTC
Description
AP26113 is an effective ALK inhibitors, IC50 was 0.62 nM, can overcome due to the effect of Crizotinib resistance of the mediated L1196M mutations. AP26113 highly effective on the sensitive and resistant H3122 cells, reduce the cell growth, inhibition of ALK, phosphate and induction of apoptosis, this effect is dose dependent. Applied to H3122 AP26113 and H3122 CR cells, reduce p - ALK, IC50 were 7.4 and 16.8 nM. AP26113 role in expressing wild-type and mutant EML4 - ALK Ba/F3 cells, reduce the cell number, 24 nM to 10 nM and IC50 respectively.
FAQ
1. WHAT services do you offer?
We can offer the Custom premixes, Semi-Finished products,.We can also assist with formulations, blends and custom packing. We are your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.
2. HOW do IÂ make an order?
Simply contact us by telephone or email.We will connect you with one of our managers who will be happy to assist you with your order.
3. WHEN will my order ship?
Products in stock usually ship within 24hours of your order being received and processed. If a product is not in stock, turnaround time varies but is generally about 1-3 weeks, depending on availability.
4. DO you sell small quantities to end users?
We accept any quantity for order, from grams to tons.
5. DO you Identity Test your Products?
Yes, we test the ID for all incoming raw materials before production of the extracts in the country of origin. Testing ID before any processing takes place helps us to deliver you the highest quality ingredients at the lowest possible prices
Â
Order Process
Step 1Â (Inquiry)
Please let me know the items you are favorable, quantities, and the destination country.Â
Step 2Â (Offer)
We offer you price and the suitable shipping method for your reference.Â
Step 3Â (Negotiation)
We will negotiate price, terms of payment, transport, delivery time, arrival time, destination of the goods and after-sales service.Â
Step 4Â (Order)
After receiving your order, we will check it and get prepared for it.Â
Step 5Â (Payment)
Please confirm the order and pay money 100% in advance, then send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements.Â
Step 6Â (Package &Â Delivery)
Parcel will be arranged within 24 hours upon receipt of your payment. And photos will be offered to tell apart the products.Â
Step 7Â (Tracking number)
If sent by EMS, the tracking number is availabe within 12 hours. The info will be trackable that day or next day.Â
If sent by HKEMS or other express, the tracking number will be provided next day. And this does not mean the info is trackable that day. It will be released on internet 2Â or 3Â days later, because the parcel has to be shipped to Hongkong fist, and then wait for the flight.Â
Step 8Â (After-Sales Service)
Within the terms of the contract, If there is any problem about the goods quality, quantity and other problems, we will assure you to make you satisfied with the results. Â
Related products
Inhibitors
MonoMethyl Dolastatin 10
203849-91-6
MMAE
474645-27-7
MMAF
745017-94-1
DM1
139504-50-0
Vandetanib
443913-73-3
nintedanib
656247-17-5
PF06463922
1454846-35-5
AZD6244/ Selumetinib
606143-52-6
INCB28060
606143-52-6
BKM120
944396-07-0Â
AZD3759
1626387-80-1
AP26113
1197958-12-5
linifanib/ABT-869
796967-16-3
AZD9291
1421373-66-1
WZ4002
1213269-23-8
dacomitinib
1110813-31-4
crizotinibÂ
877399-52-5
Regorafenib hydrate
1019206-88-2
regorafenibÂ
755037-03-7
Imatinib Mesylate
220127-57-1
Argireline Acetate
616204-22-9
Â
99% Antitumor Pharmaceutical Material Ap26113 CAS 1197958-12-5 with Fast Delivery and Good Price
Basis information
Name:AP26113
CAS:1197958-12-5
Molecular Formula:C27H36ClN6O4P
Molecular Weight:575.039301
Color:White powder
Purity:98%min
Usage: Pharmaceutical intermediates
Related Categories:Signal transduction pathway kinase inhibitor; cell signaling pathway inhibitor; protein tyrosine kinase; pharmaceutical intermediates; API; small molecule inhibitors; small molecule inhibitors, natural products
Packaging Details:on request
Delivery Detail:Shipped in 3Â days after payment
Quick details
Â
Minimum order quantity
100g
Price
Negotiable
Lead time
within 24 hours upon receipt of payment
Delivery time
About 7Â days
Packaging Details
Aluminum Foil Bags or Fiber Drum
Payment Terms
T/T,West Union, Money Gram, BTC
Description
AP26113 is an effective ALK inhibitors, IC50 was 0.62 nM, can overcome due to the effect of Crizotinib resistance of the mediated L1196M mutations. AP26113 highly effective on the sensitive and resistant H3122 cells, reduce the cell growth, inhibition of ALK, phosphate and induction of apoptosis, this effect is dose dependent. Applied to H3122 AP26113 and H3122 CR cells, reduce p - ALK, IC50 were 7.4 and 16.8 nM. AP26113 role in expressing wild-type and mutant EML4 - ALK Ba/F3 cells, reduce the cell number, 24 nM to 10 nM and IC50 respectively.
FAQ
1. WHAT services do you offer?
We can offer the Custom premixes, Semi-Finished products,.We can also assist with formulations, blends and custom packing. We are your complete source for today and tomorrow's most potent and popular natural ingredients. With experience of more than 500 formula products, if you can envision a functional product, we can make it happen.
2. HOW do IÂ make an order?
Simply contact us by telephone or email.We will connect you with one of our managers who will be happy to assist you with your order.
3. WHEN will my order ship?
Products in stock usually ship within 24hours of your order being received and processed. If a product is not in stock, turnaround time varies but is generally about 1-3 weeks, depending on availability.
4. DO you sell small quantities to end users?
We accept any quantity for order, from grams to tons.
5. DO you Identity Test your Products?
Yes, we test the ID for all incoming raw materials before production of the extracts in the country of origin. Testing ID before any processing takes place helps us to deliver you the highest quality ingredients at the lowest possible prices
Â
Order Process
Step 1Â (Inquiry)
Please let me know the items you are favorable, quantities, and the destination country.Â
Step 2Â (Offer)
We offer you price and the suitable shipping method for your reference.Â
Step 3Â (Negotiation)
We will negotiate price, terms of payment, transport, delivery time, arrival time, destination of the goods and after-sales service.Â
Step 4Â (Order)
After receiving your order, we will check it and get prepared for it.Â
Step 5Â (Payment)
Please confirm the order and pay money 100% in advance, then send us the detailed contacting information, including contacting person/company, address, mobile number, ZIP code and your special requirements.Â
Step 6Â (Package &Â Delivery)
Parcel will be arranged within 24 hours upon receipt of your payment. And photos will be offered to tell apart the products.Â
Step 7Â (Tracking number)
If sent by EMS, the tracking number is availabe within 12 hours. The info will be trackable that day or next day.Â
If sent by HKEMS or other express, the tracking number will be provided next day. And this does not mean the info is trackable that day. It will be released on internet 2Â or 3Â days later, because the parcel has to be shipped to Hongkong fist, and then wait for the flight.Â
Step 8Â (After-Sales Service)
Within the terms of the contract, If there is any problem about the goods quality, quantity and other problems, we will assure you to make you satisfied with the results. Â
Related products
Inhibitors
MonoMethyl Dolastatin 10
203849-91-6
MMAE
474645-27-7
MMAF
745017-94-1
DM1
139504-50-0
Vandetanib
443913-73-3
nintedanib
656247-17-5
PF06463922
1454846-35-5
AZD6244/ Selumetinib
606143-52-6
INCB28060
606143-52-6
BKM120
944396-07-0Â
AZD3759
1626387-80-1
AP26113
1197958-12-5
linifanib/ABT-869
796967-16-3
AZD9291
1421373-66-1
WZ4002
1213269-23-8
dacomitinib
1110813-31-4
crizotinibÂ
877399-52-5
Regorafenib hydrate
1019206-88-2
regorafenibÂ
755037-03-7
Imatinib Mesylate
220127-57-1
Argireline Acetate
616204-22-9
Â
99% Antitumor Pharmaceutical Material Ap26113 CAS 1197958-12-5 with Fast Delivery>
Model NO.: 1197958-12-5
Molecular Formula: C27H36ClN6O4P
Molecular Weight: 575.039301
Assay: 99%
Payment Terms: Western Union, Money Gram, Bank Transfer, Bitcoin
Price: negotiable
Courier: DHL, EMS, FedEx, TNT, Aramex, etc
Package: Discreet package
MOQ.: 100grams
Trademark: Zhuzhou Yuancheng
Transport Package: foil bag
Specification: 98%min.
Origin: China
HS Code: 3001909099
Model NO.: 1197958-12-5
Molecular Formula: C27H36ClN6O4P
Molecular Weight: 575.039301
Assay: 99%
Payment Terms: Western Union, Money Gram, Bank Transfer, Bitcoin
Price: negotiable
Courier: DHL, EMS, FedEx, TNT, Aramex, etc
Package: Discreet package
MOQ.: 100grams
Trademark: Zhuzhou Yuancheng
Transport Package: foil bag
Specification: 98%min.
Origin: China
HS Code: 3001909099
99% Antitumor Pharmaceutical Material Ap26113 CAS 1197958-12-5 with Fast Delivery and Good PriceNext Article
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